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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T40272 | KRAS mutant protein inhibitor 1 | ||
KRAS mutant protein inhibitor 1 is a KRAS mutant protein inhibitor for potential treatment in cancer. | |||
T77805 | KRAS G12C mutant protein inhibitor A-1 | ||
KRAS G12C mutant protein inhibitor A-1 can be used in studies about Ras. | |||
T74698 | RMC-6236 | RAS-IN-2 | |
RMC-6236(RAS-IN-2) is a potent inhibitor of RAS(ON) MULTI, utilized in cancer research [1]. | |||
T37130 | MRTX1133 formic | ||
MRTX1133 is a highly selective, first-in-class inhibitor of KRAS G12D. MRTX1133 targets the KRAS G12D protein in both active and inactive states. MRTX1133 selectively inhibits KRAS G12D mutant, but not KRAS wild-type, tu... | |||
T36641 | RAS inhibitor Abd-7 | ||
RAS inhibitor Abd-7 is a powerful compound (Kd=51 nM) that binds to RAS and inhibits the protein-protein interaction (PPI) between RAS and its effectors. By interacting with RAS within cells, RAS inhibitor Abd-7 hinders ... | |||
T76059 | SAH-SOS1A TFA | ||
SAH-SOS1A TFA is a peptide-based SOS1/KRAS protein interaction inhibitor. SAH-SOS1A TFA binds to wild-type and mutant KRAS (G12D, G12V, G12C, G12S, and Q61H) with nanomolar affinity ( EC 50 =106-175 nM). SAH-SOS1A TFA di... | |||
T36779 | NG 25 (hydrochloride hydrate) | ||
NG 25 is a type II kinase inhibitor that inhibits MAP4K2 and TAK1 (IC50s = 21.7 and 149 nM, respectively).1It also inhibits the Src family kinases Src and LYN (IC50s = 113 and 12.9 nM, respectively) and Abl family kinase... |